Adverse reactions to
XENLETA were generally
mild to moderate1,2
3.3% (21/641) of patients taking XENLETA discontinued treatment due to adverse reaction vs 3.3% (21/641) of patients taking moxifloxacin3
Adverse reactions occurring in ≥2% of patients receiving XENLETA3
Adverse Reactions | XENLETA N=273 |
moxifloxacin ± linezolid N=273 |
---|---|---|
Administration site reactionsa |
7% | 3% |
Nausea | 3% | 2% |
Hepatic enzyme elevationb |
3% | 3% |
Hypokalemia | 3% | 2% |
Insomnia | 3% | 2% |
Headache | 2% | 2% |
Adverse Reactions | XENLETA N=368 |
moxifloxacin N=368 |
---|---|---|
Diarrhea | 12% | 1% |
Nausea | 5% | 2% |
Vomiting | 3% | 1% |
Hepatic enzyme elevationb |
2% | 2% |
Adverse Reactions |
Trial 1 IV ± Oral Dosing |
Trial 2 Oral Dosing Only |
||
---|---|---|---|---|
XENLETA N=273 |
moxifloxacin ± linezolid N=273 |
XENLETA N=368 |
moxifloxacin N=368 |
|
Diarrhea | N/A | N/A | 12% | 1% |
Administration site reactionsa |
7% | 3% | N/A | N/A |
Nausea | 3% | 2% | 5% | 2% |
Hepatic enzyme elevationb |
3% | 3% | 2% | 2% |
Hypokalemia | 3% | 2% | N/A | N/A |
Insomnia | 3% | 2% | N/A | N/A |
Vomiting | N/A | N/A | 3% | 1% |
Headache | 2% | 2% | N/A | N/A |
- aAdministration site reactions include infusion site pain, infusion site phlebitis, and injection site reaction.
- bHepatic enzyme elevation includes alanine aminotransferase increased, aspartate aminotransferase increased, and liver function test increased.
Total time on XENLETA can be as short as 5 days.3
Learn more